USCA11 Case: 21-10306 Date Filed: 11/07/2022 Page: 1 of 18
[DO NOT PUBLISH]
In the
United States Court of Appeals
For the Eleventh Circuit
____________________
No. 21-10305
____________________
IN RE: ZANTAC (RANITIDINE)
PRODUCTS LIABILITY
LITIGATION
___________________________________________________
9:20-cv-80555
ARTHUR CARTEE,
Plaintiff-Appellant,
versus
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.,
PFIZER, INC.,
GLAXOSMITHKLINE LLC,
Defendants-Appellees.
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2 Opinion of the Court 21-10305
____________________
No. 21-10306
____________________
IN RE: ZANTAC (RANITIDINE)
PRODUCTS LIABILITY
LITIGATION
__________________________________________________
9:20-cv-80512-RLR
MARILYN WILLIAMS,
Plaintiff-Appellant,
versus
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.,
BOEHRINGER INGELHEIM USA CORPORATION,
WALGREENS BOOT ALLIANCE, INC.,
Defendants-Appellees.
____________________
Appeals from the United States District Court
for the Southern District of Florida
D.C. Docket No. 9:20-md-02924-RLR
____________________
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21-10305 Opinion of the Court 3
Before JORDAN and LAGOA, Circuit Judges.*
PER CURIAM:
The appellants, Arthur Cartee and Marilyn Williams, are
two of the thousands of plaintiffs alleging personal injury claims in
In re Zantac (Ranitidine), MDL No. 2924. Because there is no final
district court decision with respect to the amended complaints of
Mr. Cartee and Ms. Williams, we dismiss their appeals for lack of
appellate jurisdiction.
I
Mr. Cartee and Ms. Williams both alleged that they took
ranitidine products to treat mild heartburn. Starting in 2006, Mr.
Cartee began taking both prescription and over-the-counter ge-
neric ranitidine. He developed prostate cancer in 2012. Ms. Wil-
liams started taking Zantac, an over-the-counter brand-name drug,
in 2011. She was diagnosed with abdominal and ovarian cancer in
2016.
A
On February 6, 2020, the U.S. Judicial Panel on Multidistrict
Litigation created an MDL in the Southern District of Florida—
MDL No. 2924—for purposes of centralizing pretrial proceedings
in actions alleging that ranitidine, the active ingredient in Zantac,
* After oral argument, Judge Luck recused himself from this case. This opinion
is therefore issued by a quorum. See
28 U.S.C. § 46(d); 11th Cir. R. 34-2.
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4 Opinion of the Court 21-10305
breaks down to form an alleged carcinogen known as N-Nitrosodi-
methylamine (NDMA).
After the MDL was created, Mr. Cartee and Ms. Williams
each filed separate federal lawsuits—Mr. Cartee in Illinois and Ms.
Williams in Alabama—alleging that ranitidine caused their cancers.
Their actions were transferred to the MDL.
A few months after the transfers, the parties filed a proposed
order coordinating the filings of master complaints. This order,
known as Pretrial Order # 31, was adopted and entered by the dis-
trict court.
The Order required the personal injury plaintiffs to “file a
Master Personal Injury Complaint [or MPIC] on behalf of all Plain-
tiffs asserting personal injury claims in MDL No. 2924.” MDL D.E.
876 at 2. The Order stated that “[a]ll claims pleaded in the [MPIC]
will supersede and replace all claims pleaded in any complaint pre-
viously filed in or transferred to MDL No. 2924 . . . .”
Id.
In addition, the Order directed the personal injury plaintiffs
to attach a Master Short Form Complaint (or SFC) to serve as a
template “for each individual case.”
Id. The individual plaintiffs
were to provide certain information, such as their names, injuries,
places of residence, and the defendants being sued. See
id. The
SFCs took the form of a worksheet that allowed each plaintiff to fill
in the blanks as to who was being sued and to check boxes for
which claims were being asserted. See
id. The SFC also contained
a clause indicating that it incorporated all allegations from the
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21-10305 Opinion of the Court 5
MPIC. See
id. The Order stated that, “[f]or each action directly
filed in or transferred to MDL No. 2924 subject to this Order, the
[MPIC] together with the Short Form Complaint shall be deemed
the operative Complaint.”
Id. at 3. 1
Shortly thereafter, the personal injury plaintiffs filed the
MPIC. The MPIC named no individual plaintiffs. Instead, it incor-
porated them by reference. The MPIC states it “is not intended to
consolidate for any purpose the separate claims of the individual
Plaintiffs in this MDL,” and that it “does not constitute waiver or
dismissal of any actions or claims asserted in those individual ac-
tions.” MDL D.E. 887 at 2. The MPIC refers to the plaintiffs’ cases
as individual “actions” throughout. See
id. at ¶¶ 216, 434–35.
As directed, Mr. Cartee and Ms. Williams both filed short
form complaints to go with the MPIC.
In his SFC, Mr. Cartee sued four brand-name manufacturers
(Boehringer, GlaxoSmithKline, Sanofi, and Sanofi-Aventis) and
1 MDL No. 2924 therefore “employe[d] the device of a master complaint, sup-
plemented by individual short-form complaints that adopt the master com-
plaint in whole or in part.” In re Zofran (Ondansetron) Products Liability
Litig., MDL No. 1:15-md-2657-FDS,
2017 WL 1458193, at *6 (D. Mass. Apr. 24,
2017). The master complaint contained allegations common to all plaintiffs
asserting the same types of claims, while the short-form complaints contained
allegations specific to each individual plaintiff. See In re Taxotere (Docetexel)
Prod. Liab. Litig.,
995 F.3d 384, 387 (5th Cir. 2021). See also Manual for Com-
plex Litigation (Fourth) § 40.52 (Fed. Jud. Ctr. 2004) (providing sample case
management order governing mass tort claims using master and short-form
complaints).
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6 Opinion of the Court 21-10305
two retailers (Walgreens and Walmart). He checked the boxes for
Counts I–XIII of the MPIC, leaving out only Count XIV (a survival
action) and Count XV (a wrongful death claim). As discussed be-
low, he filed an amended SFC shortly thereafter, dropping the
Sanofi entities from the list of brand-name defendants from which
he sought to recover.
In her SFC, Ms. Williams sued two brand name manufactur-
ers (Boehringer Ingelheim Pharmaceuticals and Boehringer Ingel-
heim USA) and one retailer (Walgreens), and she indicated that any
distributors and repackagers she might sue were then unknown.
She checked the boxes for five different counts in the MPIC, includ-
ing those asserting claims for strict products liability, failure to
warn, and breaches of warranties. Like Mr. Cartee, and as dis-
cussed below, Ms. Williams later amended her SFC.
B
The district court dismissed the entire MPIC without preju-
dice as a shotgun pleading. See MDL D.E. 2515 at 13. In a separate
order, the court also held that any claims “based on an allegation
that a brand-name drug’s FDA-approved formulation renders the
drug misbranded” were preempted by the Food, Drug, and Cos-
metics Act,
21 U.S.C. § 301 et. seq., “because the drug’s manufac-
turer cannot independently and lawfully change a drug formula-
tion that the FDA has approved.” MDL D.E. 2532 at 24. The court
ordered the personal injury plaintiffs to omit misbranding allega-
tions if they amended the MPIC.
Id. at 25.
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21-10305 Opinion of the Court 7
In another order, the district court ruled that any state with-
out a supreme court decision supporting the plaintiffs’ “innovator
liability” theory of negligent misrepresentation (i.e., any state other
than Massachusetts and California) would not recognize a duty by
brand-name manufacturers to consumers of generic ranitidine. See
MDL D.E. 2516 at 14. The district court granted plaintiffs who
brought such claims against defendants in courts outside of Califor-
nia and Massachusetts leave to amend “to plead a prima facie case
of personal jurisdiction in California or Massachusetts.”
Id. at 8, 24.
The district court did not dismiss any individual SFCs.
After the MPIC was dismissed and before any amended
MPIC was filed, Mr. Cartee filed a second amended SFC. This SFC
only checked the box for Count VIII, asserting negligent misrepre-
sentation, against three of the brand name manufacturers
(Boehringer, GlaxoSmithKline, and Pfizer). The second amended
SFC eliminated all other claims and deleted the retailer defendants.
It also added the following paragraph:
Plaintiff is suing for injuries related only to generic
consumption. Plaintiff’s sole theory of liability is that
Boehringer Ingelheim Pharmaceuticals, Inc., Glax-
oSmithKline LLC, and Pfizer, Inc. negligently misrep-
resented the safety of ranitidine through their labeling
of branded Zantac, that it was foreseeable that ge-
neric manufacturers of ranitidine would copy those
misrepresentations, and that Plaintiff and his doctor
relied on those misrepresentations in consuming and
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8 Opinion of the Court 21-10305
prescribing the ranitidine that caused Plaintiff’s can-
cer and other injuries.
Cartee D.E. 19 ¶ 13. Significantly, Mr. Cartee’s second amended
SFC still purported to incorporate the allegations in the then-dis-
missed MPIC.
On the same day that he filed the second amended SFC, and
without obtaining any further ruling from the district court, Mr.
Cartee filed a notice of appeal. He cited the district court’s innova-
tor liability claims order and stated that the order “was made final
with respect to Plaintiff Arthur Cartee on the 27th day of January,
2021, when Plaintiff amended his Short Form Complaint to elimi-
nate all claims for which repleading was permitted by the Court’s
Orders.” Cartee D.E. 20. In his appeal, Mr. Cartee seeks reversal
of the district court’s rulings with respect to innovator liability un-
der Illinois law.
Ms. Williams pursued a similar strategy with one additional
wrinkle. First, she filed an amended SFC after the dismissal of the
MPIC and before the filing of an amended MPIC. In her amended
SFC, she only checked the box for the MPIC’s strict products liabil-
ity design defect claim and eliminated any suggestion that she
might sue yet-unknown distributors and repackagers. She also
added the following paragraph:
Plaintiff’s sole theory of liability is that the ranitidine
she consumed was defectively designed under state
law, and that these same design defects made
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21-10305 Opinion of the Court 9
ranitidine dangerous to health when used as in-
structed on the label such that it was misbranded un-
der federal law. The ranitidine Plaintiff consumed
was illegal to sell under federal law, and requires com-
pensation under state design defect tort law.
Williams D.E. 12 at ¶ 13. Ms. Williams’ amended SFC also incor-
porated the allegations in the then-dismissed MPIC.
On the same day that she filed her amended SFC, Ms. Wil-
liams voluntarily dismissed it without prejudice pursuant to Fed-
eral Rule of Civil Procedure 41(a)(1)(A)(i). Ms. Williams then filed
a notice of appeal, indicating that she wished to appeal the district
court’s orders granting the defendants’ motions to dismiss “on
preemption grounds,” and asserted that “[t]hese [o]rders were
made final with respect to Plaintiff Marilyn Williams on the 27th
day of January, 2021, when Plaintiff amended her Short Form
Complaint to eliminate all claims for which repleading was permit-
ted by the Court’s Orders.” Williams D.E. 14 at 1. On appeal, Ms.
Williams argues that where a plaintiff pleads a design defect in a
drug based on post-approval scientific evidence never presented to
the FDA, that state-law claim is not preempted by the FDCA. 2
After Mr. Cartee and Ms. Williams filed their notices of ap-
peal, the personal injury plaintiffs filed an amended MPIC. The
2The district court subsequently deconsolidated Ms. Williams’ case from the
MDL proceeding in light of her notice of voluntary dismissal.
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10 Opinion of the Court 21-10305
district court has subsequently granted Rule 54(b) judgments in fa-
vor of some defendants on some or all of the claims against them,
including Walgreens—the retailer Ms. Williams is suing. A second
amended MPIC remains pending against the brand-name defend-
ants.
II
Courts of appeals have subject-matter jurisdiction over “ap-
peals from all final decisions of the district courts of the United
States.”
28 U.S.C. § 1291. Under § 1291, “[a] ‘final decision’ is one
by which a district court disassociates itself from a case.” Gelboim
v. Bank of Am. Corp.,
574 U.S. 405, 408 (2015) (internal quotation
marks omitted). “[T]he statute’s core application is to rulings that
terminate an action.”
Id. at 409.
The defendants ask us to dismiss the appeals of Mr. Cartee
and Ms. William for lack of appellate jurisdiction because the or-
ders dismissing the MPIC—which they argue merged the personal
injury cases against them—are non-final and non-appealable. Mr.
Cartee and Ms. Williams respond that the personal injury plaintiffs’
actions are merely consolidated and their individual rights to ap-
peal are unaffected by the structure of this MDL.
A
We conclude that we lack jurisdiction to consider Mr. Car-
tee’s appeal. Simply stated, there is no final decision in the district
court against Mr. Cartee.
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21-10305 Opinion of the Court 11
Under § 1291, “an order that disposes of fewer than all of the
claims against all of the parties is not immediately appealable.”
Commodores Ent. Corp. v. McClary,
879 F.3d 1114, 1126 (11th Cir.
2018) (emphasis added). See also Fed. R. Civ. P. 54(b) (when an
action involves multiple claims or parties, an order “that adjudi-
cates fewer than all the claims or the rights and liabilities of fewer
than all the parties” ordinarily “does not end the action as to any of
the claims or parties”). “[A]n order dismissing a complaint with
leave to amend within a specified time becomes a final judgment if
the time allowed for amendment expires without the plaintiff seek-
ing an extension.” Auto. Alignment & Body Serv., Inc. v. State
Farm Mut. Auto. Ins. Co.,
953 F.3d 707, 719–20 (11th Cir. 2020).
But if a plaintiff chooses to file an amended complaint, that party
may not also appeal the dismissal order at that time. See Fuller v.
Carollo,
977 F.3d 1012, 1014 (11th Cir. 2020) (dismissing appeal of
qualified immunity order for lack of jurisdiction where the plain-
tiffs elected to file an amended complaint after the ruling); Lobo v.
Celebrity Cruises, Inc.,
2009 WL 6353884, at *1 (11th Cir. Dec. 16,
2009) (“The district court’s [dismissal order] is not final or immedi-
ately appealable because the plaintiffs elected to file an amended
complaint prior to filing their . . . notice of appeal.”).
As explained earlier, Mr. Cartee’s operative complaint in-
cludes two documents: the MPIC and his SFC. After the MPIC was
dismissed, Mr. Cartee filed a second amended SFC eliminating all
but one of his claims and adding language clarifying the scope of
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12 Opinion of the Court 21-10305
his action. At the time he filed the second amended SFC, it pur-
ported to incorporate the allegations of the MPIC, but there was
no operative MPIC to incorporate because the MPIC had been dis-
missed. The personal injury plaintiffs filed an amended MPIC,
which restructured the claims and eliminated certain factual allega-
tions, but they did so after Mr. Cartee filed a notice of appeal. A
second amended MPIC remains pending in the district court today,
as does Mr. Cartee’s second amended SFC. Indeed, Mr. Cartee
could file a third amended SFC today incorporating the second
amended MPIC and selecting a new combination of claims to as-
sert.
An individual plaintiff like Mr. Cartee does not necessarily
need to wait for the resolution of the entire MDL to appeal. The
district court could dismiss his amended SFC sua sponte (or on mo-
tion) in light of its rulings on the MPIC, but it has not done that.
The district court could also enter a Rule 54(b) judgment against
Mr. Cartee or in favor of the defendants Mr. Cartee is suing. But it
has not done that either and Mr. Cartee has not asked for a such a
judgment. See Ryan v. Occidental Petroleum Corp.,
577 F.2d 298,
302 (5th Cir. 1978) (“But where the claim is complete in itself and
where the adjudication of that claim is also complete, Rule 54(b)
certification is the appropriate channel for assuring appealability.”).
Mr. Cartee claims that his individual case is “conclusively
over.” Cartee Jurisdictional Response at 9. He predicts that, if the
district court looked at his second amended SFC, it would
acknowledge that his remaining claim is due to be dismissed under
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21-10305 Opinion of the Court 13
its rulings on innovator liability claims outside of Massachusetts
and California. See
id. at 8–9. That prediction may turn out to be
correct, but the district court had no opportunity to enter any final
judgment because Mr. Cartee filed a notice of appeal the very day
he filed the second amended SFC and at a time when there was no
MPIC to incorporate. He cannot unilaterally declare his second
amended SFC dead when the district court has not done so, and he
cannot deny that this SFC is still alive and pending in the district
court. See, e.g., Occidental Petroleum Corp.,
577 F.2d at 302
(“[T]hese partial rulings on his complaint, considered together with
the purported voluntary dismissal of [one paragraph of the com-
plaint], do not amount to a termination of the litigation between
the parties.”). Because there is no final ruling against his operative
complaint—the combination of the MPIC and his SFC—to put the
last nail in the coffin of his action, we lack jurisdiction to consider
Mr. Cartee’s appeal.
B
Ms. Williams’ voluntary dismissal of her own amended SFC
did not have the effect of creating a final judgment. We therefore
also lack jurisdiction over her appeal.
A “Rule 41(a)(1) voluntary dismissal without prejudice is not
ordinarily appealable.” Univ. of S. Ala. v. Am. Tobacco Co.,
168
F.3d 405, 408 n.1 (11th Cir. 1999). See also 15A Charles Alan
Wright & Arthur R. Miller, Fed. Prac. & Proc. § 3914.8 (2d ed. &
April 2022 update) (“[A] voluntary dismissal without prejudice gen-
erally fails to achieve finality.”). But “[o]ur precedent splinters in
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14 Opinion of the Court 21-10305
multiple directions on whether voluntary dismissals without prej-
udice are final.” Corley v. Long-Lewis, Inc.,
965 F.3d 1222, 1228
(11th Cir. 2020). Compare, e.g., State Treasurer v. Barry,
168 F.3d
8, 13 (11th Cir. 1999) (“[V]oluntary dismissals, granted without
prejudice, are not final decisions themselves . . . .”), with, e.g., CSX
Transp., Inc. v. City of Garden City,
235 F.3d 1325, 1328–29 (11th
Cir. 2000) (concluding that a voluntary dismissal without prejudice
was final when “there was no attempt to manufacture jurisdic-
tion”). In Corley, we held that “an order granting a motion to vol-
untarily dismiss the remainder of a complaint under Rule 41(a)(2)
‘qualifies as a final judgment for purposes of appeal.’” 965 F.3d at
1231 (citations omitted).
In this case, however, Ms. Williams is seeking to appeal mat-
ters related to the very claim she voluntarily dismissed through
Rule 41(a)(1). She wants to challenge the district court’s preemp-
tion ruling regarding the “misbranding” theory of design defect li-
ability. And she argues that the district court’s preemption orders
“terminated her entire action.” Williams Jurisdictional Response
at 6. But there is no final order from the district court on Ms. Wil-
liams’ design defect claim. There is also no final order dismissing
the design defect claims in the later-filed second amended MPIC.
That MPIC remains pending in the district court and includes two
design defect claims—one based on the drug’s warnings and pre-
cautions and another based on allegedly improper expiration dates.
See MDL D.E. 3887 at 230–312.
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21-10305 Opinion of the Court 15
Like Mr. Cartee, Ms. Williams filed an amended SFC incor-
porating allegations from the MPIC which had been dismissed. She
then dismissed that very same amended SFC without any further
action or acknowledgement from the district court. Because Ms.
Williams’ amended SFC was pending when she voluntarily dis-
missed it and because there was no operative MPIC in place to
combine with the amended SFC, there was necessarily no final
judgment against Ms. Williams. Ms. Williams’ subjective belief
that the district court would dismiss her amended SFC—which
merely checks the box for the dismissed MPIC’s design defect claim
and purports to base itself solely on the MPIC’s misbranding the-
ory—does not make a final judgment. We find it hard to classify
Ms. Williams’ voluntary dismissal of her amended SFC as anything
other than an attempt to “manufacture jurisdiction.” See CSX
Transp., Inc., 235 F.3d at 1328.
Ms. Williams also argues that her Rule 41 dismissal rendered
the district court’s preemption rulings final as against her because
the district court placed “stringent conditions” on her ability to re-
plead her only remaining theory at that time—a preempted design
defect claim based on the “misbranding” theory of liability. See
Williams Jurisdictional Response at 6–9. But the district court’s or-
der did not place conditions on Ms. Williams’ filing of an amended
SFC. It placed conditions only on the MPIC, which was in fact later
amended and refiled. And, like Mr. Cartee, Ms. Williams—who
voluntarily dismissed her amended SFC without prejudice—could
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16 Opinion of the Court 21-10305
file a second amended SFC today, checking the boxes for a different
line-up of claims.
As the Corley concurrence explained, “Rule 41(a) is a poor
mechanism to accelerate appellate review.” Corley, 965 F.3d at
1236 (Pryor, C.J., concurring). It “contemplates the voluntary dis-
missal of ‘an action,’ which, we have explained, refers to ‘the whole
case’ instead of particular claims.” Id. (internal citations omitted).
See also Perry v. Schumacher Grp. of Louisiana,
891 F.3d 954, 956
(11th Cir. 2018) (“Rule 41(a)(1), according to its plain text, permits
voluntary dismissals only of entire ‘actions,’ not claims. Thus, the
invalid joint stipulation did not divest the District Court of jurisdic-
tion over the case.”). All of that is particularly true in the context
of an MDL like this one where the parties have filed an operative
master complaint. The rulings that Ms. Williams seeks to appeal
impact not only her claims, but also the claims of many of her fel-
low personal injury plaintiffs.
Ms. Williams could seek and possibly obtain a tailored Rule
54(b) judgment to break away from those other plaintiffs with the
district court’s permission, but she has instead acted unilaterally to
dismiss her own amended SFC. A Rule 41(a) voluntarily dismissal
cannot manufacture finality under such circumstances. See, e.g.,
Microsoft Corp. v. Baker,
137 S. Ct. 1702, 1715 (2017) (“Plaintiffs in
putative class actions cannot transform a tentative interlocutory or-
der . . . into a final judgment within the meaning of § 1291 simply
by dismissing their claims with prejudice—subject, no less, to the
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21-10305 Opinion of the Court 17
right to ‘revive’ those claims if the denial of class certification is re-
versed on appeal[.]”); Perry, 891 F.3d at 958 (“The existence of
[other] procedural vehicles [like a Rule 15 amendment or a Rule
54(b) partial judgment] confirms that the purpose of Rule 41(a) is
altogether different from that sought by the parties in this case.”).
After these appeals were filed, the district court entered a fi-
nal judgment in favor of all the retailer defendants, including
Walgreens, under Rule 54(b). See MDL D.E. 4665 at 1 (entering a
final judgment “on behalf of all Retailer/Pharmacy . . . Defendants
. . . against any Plaintiff who has entered a claim against [them] as
to Counts I through VI and Counts VIII through XII of the Master
Personal Injury Complaint, . . . all previously dismissed by the
Court. . .”). Ms. Williams argues that “[e]ven presuming a mono-
lithic MDL action, [that] Rule 54(b) certification has rendered the
district court’s preemption order final against Walgreens.” Wil-
liams Jurisdictional Response at 9.
We disagree. It is true that “a subsequent Rule 54(b) certifi-
cation cures a premature notice of appeal from a non-final order
dismissing claims or parties.” Nat’l Ass’n of Boards of Pharmacy v.
Bd. of Regents of the Univ. Sys. Of Georgia,
633 F.3d 1297, 1306
(11th Cir. 2011). But that does not mean that Ms. Williams’ appeal
against Walgreens has been perfected. This later Rule 54(b) judg-
ment does not change the fact that Ms. Williams voluntarily dis-
missed her amended SFC (which could not be partnered with any
viable and pending MPIC) against Walgreens. It does nothing to
revive the amended SFC that Ms. Williams voluntarily dismissed.
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18 Opinion of the Court 21-10305
III
Mr. Cartee and Ms. Williams argue that their actions are
more or less dead given the district court’s rulings dismissing cer-
tain claims from the MPIC. But “[t]here’s a big difference between
mostly dead and all dead. . . . Mostly dead is slightly alive.” The
Princess Bride (Act III Communications 1987). It may be that the
claims remaining in their amended SFCs—once paired with a via-
ble and pending MPIC—have little hope of surviving given the dis-
trict court’s rulings. But at the moment there is no final ruling put-
ting their operative complaints—the combination of the MPIC and
their individual SFCs—to rest. For that reason, we lack jurisdiction
to consider their appeals. The defendants’ motions to dismiss these
appeals are granted.
APPEALS DISMISSED.